RO<\/strong><\/p>\n\n\n\n Platform\u0103 microfluidic\u0103 multifunc\u021bional\u0103 de tipul lab-on-a-chip pentru fabricarea nanoparticulelor<\/p>\n\n\n\n <\/p>\n\n\n\n Acronim: NANOCHIP<\/p>\n\n\n\n Cod Proiect: PN-III-P1.1-TE-2019-1450<\/p>\n\n\n\n Num\u0103rul Contractului:103<\/p>\n\n\n\n Start: 07 Septembrie 2020<\/p>\n\n\n\n Final: 06 Septembrie 2022<\/p>\n\n\n\n Durata: 24 Luni<\/p>\n\n\n\n Budget: 431.900,00 RON<\/p>\n\n\n\n Autoritatea Contractant\u0103: UEFISCDI \u2013 Unitatea Executiv\u0103 pentru Finan\u021barea \u00cenv\u0103\u021b\u0103m\u00e2ntului Superior, a Cercet\u0103rii, Dezvolt\u0103rii \u0219i Inov\u0103rii<\/p>\n\n\n\n Institu\u021bie: UPB-CNMN \u2013 Universitatea POLITEHNICA din Bucure\u0219ti \u2013 Centrul Na\u021bional de Micro \u0219i Nanomateriale<\/p>\n\n\n\n Echipa proiectului<\/strong><\/p>\n\n\n\n Director: Conf. dr.ing. Alexandru Mihai GRUMEZESCU<\/p>\n\n\n\n Membru t\u00e2n\u0103r cercet\u0103tor: CS I Anton FICAI<\/p>\n\n\n\n Membru t\u00e2n\u0103r cercet\u0103tor: CS III Bogdan \u0218tefan VASILE<\/p>\n\n\n\n Membru doctorand: drd.ing. Elena Alexandra STOICA (OPREA)<\/p>\n\n\n\n Membru doctorand: drd.ing. Alexandra Cristina BURDU\u0218EL<\/p>\n\n\n\n Membru doctorand: drd.ing. Alexandra C\u0103t\u0103lina B\u00ceRC\u0102<\/p>\n\n\n\n Membru doctorand: drd.ing. Cristina CHIRCOV<\/p>\n\n\n\n Membru cercet\u0103tor Postdoctoral: ACS Vladimir Lucian ENE<\/p>\n\n\n\n Obiectivul proiectului<\/strong><\/p>\n\n\n\n Considerat\u0103 tehnologia secolului 21, nanotehnologia a cunoscut progrese extraordinare \u00een ultimii ani, cu impact multidimensional asupra societ\u0103\u021bii. Aplicarea nanotehnologiei \u00een medicin\u0103 aduce noi perspective pentru diagnosticul, preven\u021bia, tratamentul \u0219i monitorizarea bolilor. Totu\u0219i, exist\u0103 doar 50 de tipuri de nanoparticule(NP) aprobate pentru aplica\u021bii clinice, din cauza problemelor asociate care trebuie dep\u0103\u0219ite: controlul limitat al propriet\u0103\u021bilor, lipsa uniformit\u0103\u021bii, efecte imprevizibile \u00een interiorul organismului \u0219i nevoia personalului specializat pentru sintez\u0103. Prin acest proiect, propunem o solu\u021bie nou\u0103 care ar putea ajuta la progresul nanotehnologiei: dezvoltarea dispozitivelor lab-on-chip (LoC) pentru sinteza de NP \u0219i sisteme de administrare a medicamentelor. Pe baza experien\u021bei noastre anterioare, vom proiecta \u0219i fabrica un dispozitiv LoC tot-\u00eentr-unul pentru sinteza complet\u0103 a NP. Ulterior, vom dezvolta un dispozitiv LoC pentru fabricarea \u00eentr-o singur\u0103 etap\u0103 a microparticulelor polimerice care \u00eencapsuleaz\u0103 NP de magnetit\u0103. Punctul de pornire al acestui proiect este un dispozitiv LoC fabricat anterior, care s-a dovedit util pentru dezvoltarea microparticulelor polimer-polimer pentru eliberarea controlat\u0103 a moleculelor bioactive. Obiectivele proiectului nostru sunt: 1)Fabricarea dispozitivelor LoC potrivite; 2)Sinteza NP de Fe3O4 folosind dispozitivul LoC; 3)Optimizarea dispozitivului LoC pentru a elimina variabilitatea \u0219i a spori reproductibilitatea; 4)Dezvoltarea unui sistem hibrid de administrare de medicamente bazat pe microparticule polimerice care \u00eencapsuleaz\u0103 NP de Fe3O4. Materialele sintetizate vor fi caracterizate pentru a evalua propriet\u0103\u021bile lor fizico-chimice \u0219i asigura reproductibilitatea dispozitivelor LoC. Astfel, suntem \u00eencrez\u0103tori c\u0103 acest proiect poate reprezenta pasul ini\u021bial \u00een progresul nanotehnologiei, oferind mijloace de sintez\u0103 standardizate a nanomaterialelor \u0219i avans\u00e2nd de la conceptul de variabilitate spre reproductibilitate.<\/p>\n\n\n\n Plan de lucru<\/strong><\/p>\n\n\n\n Etapa 1<\/strong><\/em><\/p>\n\n\n\n Dispozitiv de tip LoC, utiliz\u00e2nd date de literatur\u0103, pentru sinteza nanoparticulelor de magnetit\u0103<\/p>\n\n\n\n \u2022 Sinteza nanoparticulelor de magnetita folosind dispozitivul LoC<\/p>\n\n\n\n \u2022 Caracterizarea (prin TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) a nanoparticulelor sintetizate<\/p>\n\n\n\n Etapa 2<\/em><\/strong><\/p>\n\n\n\n Proiectarea,fabricarea si testarea dispozitivului LoC prin sinteza nanoparticulelor de magnetit\u0103<\/p>\n\n\n\n \u2022 Proiectarea unui dispozitiv LoC pentru sinteza nanoparticulelor de magnetita<\/p>\n\n\n\n \u2022 Fabricarea \u0219i caracterizarea (prin microscopie) a dispozitivului LoC pentru sinteza nanoparticulelor de magnetita<\/p>\n\n\n\n \u2022 Sinteza nanoparticulelor de magnetita folosind dispozitivul LoC nou fabricat<\/p>\n\n\n\n \u2022 Caracterizarea (prin TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) a nanoparticulelor sintetizate<\/p>\n\n\n\n \u2022 Optimizarea dispozitivului LoC<\/p>\n\n\n\n \u2022 Sinteza nanoparticulelor utiliz\u00e2nd dispozitivul LoC optimizat<\/p>\n\n\n\n \u2022 Caracterizarea (prin TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) a nanoparticulelor sintetizate<\/p>\n\n\n\n Etapa 3<\/em><\/strong><\/p>\n\n\n\n Dezvoltarea unui sistem polimeric hibrid pentru livrarea de medicamente care \u00eencapsuleaz\u0103 nanoparticulele func\u021bionalizate folosind dispozitivul LoC<\/p>\n\n\n\n \u2022 Proiectarea unui dispozitiv LoC pentru sinteza microparticulelor polimerice care \u00eencapsuleaz\u0103 nanoparticulele de magnetit\u0103<\/p>\n\n\n\n \u2022 Fabricarea dispozitivului LoC pentru sinteza microparticulelor polimerice care \u00eencapsuleaz\u0103 nanoparticulele de magnetit\u0103<\/p>\n\n\n\n \u2022 Sinteza microparticulelor polimerice care \u00eencapsuleaz\u0103 nanoparticulele de magnetit\u0103 folosind dispozitivul LoC<\/p>\n\n\n\n \u2022 Caracterizarea (prin TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) a microparticulelor polimerice sintetizate care \u00eencapsuleaz\u0103nanoparticulele de magnetit\u0103<\/p>\n\n\n\n \u2022 Optimizarea dispozitivului LoC<\/p>\n\n\n\n \u2022 Sinteza microparticulelor polimerice care \u00eencorporeaz\u0103 nanoparticulele utiliz\u00e2nd dispozitivul LoC optimizat<\/p>\n\n\n\n Caracterizarea (prin TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) a microparticulelor polimerice sintetizate<\/p>\n\n\n\n Diseminarea rezultatelor<\/p>\n\n\n\n Tabelul 1.<\/strong> Lista articolelor \u0219tiin\u021bifice publicate \u00een cadrul proiectului.<\/p>\n\n\n\n Tabelul 2.<\/strong> Lista conferin\u021belor la care au fost diseminate rezultatele ob\u021binute \u00een cadrul proiectului.<\/p>\n\n\n\n \u00cen urma tuturor analizelor, s-a demonstrat eficien\u021ba crescut\u0103 a metodelor microfluidice \u00een sinteza MNPs \u0219i al nanomaterialelor \u00een general. Pe l\u00e2ng\u0103 ob\u021binerea unor propriet\u0103\u021bi ale nanoparticulelor standardizate \u0219i uniforme, utilizarea dispozitivelor LoC reduce timpul de sintez\u0103, simplific\u0103 \u0219i eficientizeaz\u0103 procesul de sp\u0103lare \u0219i separ\u0103 MNPs cu propriet\u0103\u021bi magnetice de cele non-magnetice, elimin\u00e2nd influen\u021ba gravita\u021biei \u00een procesul de separare \u0219i purificare al acestora. Mai mult dec\u00e2t at\u00e2t, versatilitatea metodelor microfluidice ofer\u0103 posibilitatea proiect\u0103rii \u0219i fabric\u0103rii unei variet\u0103\u021bi largi de configura\u021bii ale microcanalelor \u00een func\u021bie de necesit\u0103\u021bile fiec\u0103rei sinteze \u00een parte, aceasta reprezent\u00e2nd impactul major dat de implementarea prezentului proiect.<\/p>\n\n\n\n <\/p>\n\n\n\n EN<\/strong><\/p>\n\n\n\n Multifunctional lab-on-a-chip microfluidic platform for the fabrication of nanoparticles<\/p>\n\n\n\n Abbreviation: NANOCHIP<\/p>\n\n\n\n Project code: PN-III-P1.1-TE-2019-1450<\/p>\n\n\n\n Contract number: 103<\/p>\n\n\n\n Start: 07 September 2020<\/p>\n\n\n\n End: 06 September 2022<\/p>\n\n\n\n Duration: 24 months<\/p>\n\n\n\n Budget: 431.900,00 RON<\/p>\n\n\n\n Contracting authority: UEFISCDI – Executive Unit for Financing Higher Education, Research, Development and Innovation<\/p>\n\n\n\n Coordinating institution: UPB-CNMN \u2013 University POLITEHNICA of Bucharest \u2013 National Center for Micro and Nanomaterials<\/p>\n\n\n\n Project team<\/strong><\/p>\n\n\n\n Project manager: Assoc.Prof.PhD.Eng. Alexandru Mihai GRUMEZESCU<\/p>\n\n\n\n Early-stage researcher: RSI Anton FICAI<\/p>\n\n\n\n Early-stage researcher: RSIII Bogdan \u0218tefan VASILE<\/p>\n\n\n\n PhD student: Eng. Elena Alexandra STOICA (OPREA)<\/p>\n\n\n\n PhD student: Eng. Alexandra Cristina BURDU\u0218EL<\/p>\n\n\n\n PhD student: Eng. Alexandra C\u0103t\u0103lina B\u00ceRC\u0102<\/p>\n\n\n\n PhD student: Eng. Cristina CHIRCOV<\/p>\n\n\n\n Postdoctoral researcher: SRA Vladimir Lucian ENE<\/p>\n\n\n\n Project objective<\/strong><\/p>\n\n\n\n Considered the technology of the 21st century, nanotechnology has witnessed tremendous advancements in the recent years, with multidimensional impacts to society. The application of nanotechnology in the health care system brings new prospect for the diagnosis, prevention, treatment, and follow-up of various diseases. However, there are only 50 types of nanoparticles (NPs) approved for clinical use, as there are still some issues that need to be overcome: limited control of the properties, lack of uniformity, unpredictable effects inside the body, and need of specialized personnel for the synthesis processes. Through this project, we propose a potential solution that could revolutionize nanotechnology: the development of lab-on-chip (LoC) devices for the synthesis of NPs and drug delivery systems. Based on our previous experience, we will focus on the design and fabrication of an all-in-one LoC device for the synthesis of ready-to-use magnetite NPs. Further, we will develop a LoC device for the one-step fabrication of polymeric microparticles encapsulating magnetite NPs. The starting point is our previously manufactured LoC device which has been proved useful for developing polymer-polymer microparticles for the controlled release of bioactive molecules. The objectives of our project are: 1) Fabrication of suitable LoC devices; 2) Synthesis of magnetite NPs using the LoC device; 3) Optimization of the LoC device to eliminate the variability and enhance reproducibility; 4) Development of a hybrid drug delivery system based on polymeric microparticles encapsulating magnetite NPs. All the synthesized materials will be characterized in order to assess their precise physico-chemical properties and ensure the reproducibility of our devices. Thus, we are confident that this project represents the initial step in revolutionizing nanotechnology by providing the means to synthesize standardized nanomaterials and advancing from the concept of variability towards reproducibility.<\/p>\n\n\n\n Working plan<\/strong><\/p>\n\n\n\n Stage 1<\/em><\/strong><\/p>\n\n\n\n LoC device, using literature information, for the synthesis of magnetite nanoparticles<\/p>\n\n\n\n \u2022 Synthesis of magnetite nanoparticles using the LoC device<\/p>\n\n\n\n \u2022 Characterization (through TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) of the synthesized nanoparticles<\/p>\n\n\n\n Stage 2<\/em><\/strong><\/p>\n\n\n\n Design, fabrication and testing of an LoC device through the synthesis of magnetite nanoparticles<\/p>\n\n\n\n \u2022 Design of an LoC device for the synthesis of magnetite nanoparticles<\/p>\n\n\n\n \u2022 Fabrication and characterization (by microscopy) of the LoC device for the synthesis of magnetite nanoparticles<\/p>\n\n\n\n \u2022 Synthesis of magnetite nanoparticles using the novel LoC device<\/p>\n\n\n\n \u2022 Characterization (by TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) of the synthetized magnetite nanoparticles<\/p>\n\n\n\n \u2022 Optimization of the LoC device<\/p>\n\n\n\n \u2022 Synthesis of magnetite nanoparticles using the optimized LoC device<\/p>\n\n\n\n \u2022 Characterization (by TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) of synthetized magnetite nanoparticles<\/p>\n\n\n\n Stage 3<\/em><\/strong><\/p>\n\n\n\n Development of a hybrid polymeric drug delivery system incorporating functionalized nanoparticles using the LoC device<\/p>\n\n\n\n \u2022 Design of a LoC device for the synthesis of polymeric microparticles encapsulating magnetite nanoparticles<\/p>\n\n\n\n \u2022 Fabrication of the LoC device for the synthesis of polymeric microparticles encapsulating magnetite nanoparticles<\/p>\n\n\n\n \u2022 Synthesis of polymeric microparticles encapsulating magnetite nanoparticles using the LoC device<\/p>\n\n\n\n \u2022 Characterization (by TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) of the synthesized polymeric microparticles encapsulating magnetite nanoparticles<\/p>\n\n\n\n \u2022 Optimization of the LoC device<\/p>\n\n\n\n \u2022 Synthesis of polymeric microparticles encapsulating magnetite nanoparticles using the optimized LoC device<\/p>\n\n\n\n \u2022 Characterization (by TEM, SAED, EDAX, SEM, XRD, FT-IR, DTA-TG) of the synthetized polymeric microparticles <\/p>\n\n\n\n Results dissemination<\/p>\n\n\n\n Table 1.<\/strong> List of scientific articles published within the project.<\/p>\n\n\n\n Table 2.<\/strong> The list of conferences where the results obtained within the project were disseminated.<\/p>\n\n\n\n Following all analyses, the increased efficiency of microfluidic methods in the synthesis of MNPs and nanomaterials, in general, was demonstrated. In addition to obtaining standardized and uniform nanoparticle properties, using LoC devices reduces synthesis time, simplifies and streamlines the washing process, and separates MNPs with magnetic properties from non-magnetic ones, eliminating the influence of gravity in their separation and purification process. Moreover, the versatility of microfluidic methods offers the possibility of designing and manufacturing a wide variety of microchannel configurations according to the needs of each synthesis, representing the major impact given by the implementation of this project.<\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" RO Platform\u0103 microfluidic\u0103 multifunc\u021bional\u0103 de tipul lab-on-a-chip pentru fabricarea nanoparticulelor Acronim: NANOCHIP Cod Proiect: PN-III-P1.1-TE-2019-1450 Num\u0103rul Contractului:103 Start: 07 Septembrie 2020 Final: 06 Septembrie 2022 Durata: 24 Luni Budget: 431.900,00 RON Autoritatea Contractant\u0103: UEFISCDI \u2013 Unitatea Executiv\u0103 pentru Finan\u021barea \u00cenv\u0103\u021b\u0103m\u00e2ntului Superior, a Cercet\u0103rii, Dezvolt\u0103rii \u0219i Inov\u0103rii Institu\u021bie: UPB-CNMN \u2013 Universitatea POLITEHNICA din Bucure\u0219ti \u2013 Centrul… Continue reading →<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":339,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-833","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/pages\/833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/grumezescu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=833"}],"version-history":[{"count":11,"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/pages\/833\/revisions"}],"predecessor-version":[{"id":855,"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/pages\/833\/revisions\/855"}],"up":[{"embeddable":true,"href":"https:\/\/grumezescu.com\/index.php?rest_route=\/wp\/v2\/pages\/339"}],"wp:attachment":[{"href":"https:\/\/grumezescu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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\n\n\n\nTitlu<\/strong><\/td> Autori<\/strong><\/td> Jurnal<\/strong><\/td> Factor de impact<\/strong><\/td><\/tr><\/thead> Synthesis of Magnetite Nanoparticles through a Lab-On-Chip Device (10.3390\/ma14195906)<\/td> Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu, Bogdan Stefan Vasile, Ovidiu Oprea, Adrian Ionut Nicoar\u0103, Chih-Hui Yang, K.C. Huang, Ecaterina Andronescu<\/td> Materials<\/td> 3,748<\/td><\/tr> Biosensors-on-Chip: An Up-to-Date Review (10.3390\/molecules25246013)<\/td> Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu, Ecaterina Andronescu<\/td> Molecules<\/td> 4,927<\/td><\/tr> Fabrication and Applications of Microfluidic Devices: A Review (10.3390\/ijms22042011)<\/td> Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu<\/td> International Journal of Molecular Sciences<\/td> 6,208<\/td><\/tr> Polymeric Nanoparticles for Antimicrobial Therapies: An Up-To-Date Overview (10.3390\/polym13050724)<\/td> Vera Alexandra Spirescu, Cristina Chircov, Alexandru Mihai Grumezescu, Ecaterina Andronescu<\/td> Polymers<\/td> 4,967<\/td><\/tr> Nanomaterials Synthesis through Microfluidic Methods: An Updated Overview (10.3390\/nano11040864)<\/td> Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu<\/td> Nanomaterials<\/td> 5,719<\/td><\/tr> Magnetite Nanoparticles: Synthesis Methods \u2013 A Comparative Review (10.1016\/j.ymeth.2021.04.018)<\/td> Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu<\/td> Methods<\/td> 4,647<\/td><\/tr> Polymer-Based Nanosystems\u2014A Versatile Delivery Approach (10.3390\/ma14226812)<\/td> Adelina-Gabriela Niculescu, Alexandru Mihai Grumezescu<\/td> Materials<\/td> 3,748<\/td><\/tr> Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies (10.3390\/ijms21197355)<\/td> Antonio David Mihai, Cristina Chircov, Alexandru Mihai Grumezescu, Alina Maria Holban<\/td> International Journal of Molecular Sciences<\/td> 6,208<\/td><\/tr> Microfluidic Synthesis of -NH2<\/sub>– and -COOH-functionalized Magnetite Nanoparticles (10.3390\/nano12183160)<\/td> Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Bogdan Stefan Vasile, Ovidiu-Cristian Oprea, Alexandru Mihai Grumezescu<\/td> Nanomaterials<\/td> 5,719<\/td><\/tr> A Review of Microfluidic Experimental Designs for Nanoparticle Synthesis (10.3390\/ijms23158293)<\/td> Adelina Gabriela Niculescu, Dan Eduard Mihaiescu, Alexandru Mihai Grumezescu<\/td> International Journal of Molecular Sciences<\/td> 6,208<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n Titlu<\/strong><\/td> Autori<\/strong><\/td> Institu\u021bie<\/strong><\/td> Edi\u021bie<\/strong><\/td><\/tr> Standardized synthesis of iron oxide nanoparticles through lab-on-chip devices<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Anton Ficai, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> E-MRS<\/td> Spring Meeting 2021<\/td><\/tr> -NH2<\/sub>– and -COOH-functionalized iron oxide nanoparticles obtained through a lab-on-chip device<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Alexandra Catalina Birca, Anton Ficai, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> E-MRS<\/td> Fall Meeting 2021<\/td><\/tr> -COOH-functionalized magnetite nanoparticles synthesized through a microfluidic lab-on-chip device<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Alexandra Catalina Birca, Anton Ficai, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> E-MRS<\/td> Spring Meeting 2022<\/td><\/tr> Microfluidic synthesis of amino- and carboxyl-functionalized magnetite nanoparticles<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Alexandra Catalina Birca, Ovidiu Cristian Oprea, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> ICC9, ECerS, Electro Ceramics<\/td> Ceramics in Europe 2022<\/td><\/tr> Microfluidic synthesis of dextran-coated magnetite nanoparticles<\/td> Cristina Chircov, Andrei Ilie, Bogdan Stefan Vasile, Ovidiu Cristian Oprea, Alexandra Catalina Birca, Ecaterina Andronescu, Alexandru Mihai Grumezescu<\/td> RICCCE 2022<\/td> RICCCE 22 \u2013 22nd Romanian International Conference on Chemistry and Chemical Engineering 2022<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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\n\n\n\nTitle<\/strong><\/td> Authors<\/strong><\/td> Journal<\/strong><\/td> Impact factor<\/strong><\/td><\/tr><\/thead> Synthesis of Magnetite Nanoparticles through a Lab-On-Chip Device (10.3390\/ma14195906)<\/td> Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu, Bogdan Stefan Vasile, Ovidiu Oprea, Adrian Ionut Nicoar\u0103, Chih-Hui Yang, K.C. Huang, Ecaterina Andronescu<\/td> Materials<\/td> 3,748<\/td><\/tr> Biosensors-on-Chip: An Up-to-Date Review (10.3390\/molecules25246013)<\/td> Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu, Ecaterina Andronescu<\/td> Molecules<\/td> 4,927<\/td><\/tr> Fabrication and Applications of Microfluidic Devices: A Review (10.3390\/ijms22042011)<\/td> Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu<\/td> International Journal of Molecular Sciences<\/td> 6,208<\/td><\/tr> Polymeric Nanoparticles for Antimicrobial Therapies: An Up-To-Date Overview (10.3390\/polym13050724)<\/td> Vera Alexandra Spirescu, Cristina Chircov, Alexandru Mihai Grumezescu, Ecaterina Andronescu<\/td> Polymers<\/td> 4,967<\/td><\/tr> Nanomaterials Synthesis through Microfluidic Methods: An Updated Overview (10.3390\/nano11040864)<\/td> Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu<\/td> Nanomaterials<\/td> 5,719<\/td><\/tr> Magnetite Nanoparticles: Synthesis Methods \u2013 A Comparative Review (10.1016\/j.ymeth.2021.04.018)<\/td> Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Alexandru Mihai Grumezescu<\/td> Methods<\/td> 4,647<\/td><\/tr> Polymer-Based Nanosystems\u2014A Versatile Delivery Approach (10.3390\/ma14226812)<\/td> Adelina-Gabriela Niculescu, Alexandru Mihai Grumezescu<\/td> Materials<\/td> 3,748<\/td><\/tr> Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies (10.3390\/ijms21197355)<\/td> Antonio David Mihai, Cristina Chircov, Alexandru Mihai Grumezescu, Alina Maria Holban<\/td> International Journal of Molecular Sciences<\/td> 6,208<\/td><\/tr> Microfluidic Synthesis of -NH2<\/sub>– and -COOH-functionalized Magnetite Nanoparticles (10.3390\/nano12183160)<\/td> Cristina Chircov, Alexandra C\u0103t\u0103lina B\u00eerc\u0103, Bogdan Stefan Vasile, Ovidiu-Cristian Oprea, Alexandru Mihai Grumezescu<\/td> Nanomaterials<\/td> 5,719<\/td><\/tr> A Review of Microfluidic Experimental Designs for Nanoparticle Synthesis (10.3390\/ijms23158293)<\/td> Adelina Gabriela Niculescu, Dan Eduard Mihaiescu, Alexandru Mihai Grumezescu<\/td> International Journal of Molecular Sciences<\/td> 6,208<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n Title<\/strong><\/td> Authors<\/strong><\/td> Conference<\/strong><\/td> Edition<\/strong><\/td><\/tr> Standardized synthesis of iron oxide nanoparticles through lab-on-chip devices<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Anton Ficai, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> E-MRS<\/td> Spring Meeting 2021<\/td><\/tr> -NH2<\/sub>– and -COOH-functionalized iron oxide nanoparticles obtained through a lab-on-chip device<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Alexandra Catalina Birca, Anton Ficai, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> E-MRS<\/td> Fall Meeting 2021<\/td><\/tr> -COOH-functionalized magnetite nanoparticles synthesized through a microfluidic lab-on-chip device<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Alexandra Catalina Birca, Anton Ficai, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> E-MRS<\/td> Spring Meeting 2022<\/td><\/tr> Microfluidic synthesis of amino- and carboxyl-functionalized magnetite nanoparticles<\/td> Cristina Chircov, Alexandru Mihai Grumezescu, Alexandra Catalina Birca, Ovidiu Cristian Oprea, Bogdan Stefan Vasile, Ecaterina Andronescu<\/td> ICC9, ECerS, Electro Ceramics<\/td> Ceramics in Europe 2022<\/td><\/tr> Microfluidic synthesis of dextran-coated magnetite nanoparticles<\/td> Cristina Chircov, Andrei Ilie, Bogdan Stefan Vasile, Ovidiu Cristian Oprea, Alexandra Catalina Birca, Ecaterina Andronescu, Alexandru Mihai Grumezescu<\/td> RICCCE 2022<\/td> RICCCE 22 \u2013 22nd Romanian International Conference on Chemistry and Chemical Engineering 2022<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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