The anti-bacterial activity of magnetic nanofluid: Fe3O4 / oleic acid / cephalosporins – core/shell/adsorbtion-shell proved on S. aureus and E. coli and possible applications as drug delivery systems.

Overview

Alice Sandra Buteicǎ, Dan Eduard Mihaiescu, Alexandru Mihai Grumezescu, Bogdan Stefan Vasile, Alexandru Popescu, Oana Maria Mihaiescu, Roridca CristescuThe anti-bacterial activity of magnetic nanofluid: Fe3O4 / oleic acid / cephalosporins – core/shell/adsorbtion-shell proved on S. aureus and E. coli and possible applications as drug delivery systems. Digest Journal of Nanomaterials and Biostructures, 5(4):927-932, 2010.

ABSTRACT

Using this system as active compound carrier, the anti-bacterial activity of the Fe3O4/oleic acid/cephalosporins nanoparticles (core/shell/adsorption-shell) on S. aureus and E. coli was tested. The dimensions of Fe3O4 nanoparticles were in the 5-20 nm range and they were characterized by High Resolution Transmision Electron Microscopy. The antibacterial activity was observed in both, reference Fe3O4/oleic acid shell nanoparticles and adsorption shell cephalosporins case. These nanofluids may be used in drug delivery systems.

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