Syntehsis, characterization and biological evaluation of Fe3O4/C12 core/shell nanosystem.


Alexandru Mihai Grumezescu, Ecaterina Andronescu, Anton Ficai, Dan Eduard Mihaiescu, Bogdan Stefan Vasile, Coralia Bleotu; Syntehsis, characterization and biological evaluation of Fe3O4/C12 core/shell nanosystem. Letters in Applied NanoBioScience, 1(2):31-35, 2012.


Lauric acid (C12) functionalized Fe3O4 nanoparticles were fabricated and characterized by XRD, FT-IR, DTA-TG and TEM. Lauric acid was used as a coating agent, controlling particle size and aggregation during the synthesis. XRD confirms the formation of magnetite. FT-IR evidenced the successful surface fictionalization with C12, peaks assigned to lauric acid being identified in the nanopowder. The obtained core/shell nanostructure consists of spherical particles of several nanometers long, according to TEM characterization. The interaction with HEp2 cell line proved that Fe3O4/C12 nanostructures are biocompatible.