Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilms development.

Overview

Ion Anghel, Alina Maria Holban, Alexandru Mihai Grumezescu*, Ecaterina Andronescu, Anton Ficai, Alina Georgiana Anghel, Maria Maganu, Veronica Lazar, Mariana Carmen Chifiriuc: Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilms development. Nanoscale Research Letters, 7:690, 2012.

ABSTRACT

This paper reports a newly fabricated nanophyto-modified wound dressing with microbicidal and anti-adherence properties. Nanofluid-based magnetite doped with eugenol or limonene was used to fabricate modified wound dressings. Nanostructure coated materials were characterized by TEM, XRD, and FT-IR. For the quantitative measurement of biofilm-embedded microbial cells, a culture-based method for viable cell count was used. The optimized textile dressing samples proved to be more resistant to staphylococcal and pseudomonal colonization and biofilm formation compared to the uncoated controls. The functionalized surfaces for wound dressing seems to be a very useful tool for the prevention of wound microbial contamination on viable tissues.

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