Alexandru Mihai Grumezescu, Ecaterina Andronescu, Anton Ficai, Chih-Hui Yang, Keng-Shiang Huang, Bogdan Stefan Vasile, Georgeta Voicu, Dan Eduard Mihaiescu, Coralia Bleotu: Magnetic nanofluid with antitumoral properties. Letters in Applied NanoBioScience, 1(3):56-60, 2012.
The present study deals with the synthesis and characterization of magnetic nanofluid and it’s in vitro anti-cancer activity against HEp2 cells. The magnetic nanofluid with an average size of 10 nm was synthesized via a modified precipitation technique and characterized by FT-IR, XRD, DTA-TG and TEM. After 24 h incubation of HEp2 with the magnetic nanofluid, significant changes in the cell morphology were discernible in fluorescent microscopy. Cytotoxicity assay shows that the magnetic nanofluid exhibits significant cytotoxicity against HEp2, 50% of thee cells being killed after 24 hours incubation with magnetic nanofluid without any external alternating magnetic field.