Influence of magnetic MWCNTs on the antimicrobial activity of cephalosporins.


Alexandru Mihai Grumezescu, Ecaterina Ilinca, Carmen Chifiriuc, Dan Mihaiescu, Paul Balaure, Vanessa Traistaru, Grigore Mihaiescu: Influence of magnetic MWCNTs on the antimicrobial activity of cephalosporins. Biointerface Research in Applied Chemistry, 1(4):139-144, 2011.


The purpose of this study was to analyze the antimicrobial activity of cephalosporin antibiotics adsorbed on the surface of magnetic MWCNTs, against microbial cells in suspension and adhered to the substrate, in order to highlight potential improvements of antimicrobial activity parameters of these antibiotics. Magnetic MWCNTs were obtained by plasma processing and characterized by HR-TEM. The need for the discovery of such strategies is imposed by the numerous mechanisms developed by pathogenic microorganisms manage to gain resistance to the majority of currently available antibiotics.