Crina Saviuc, Alexandru Mihai Grumezescu, Otilia Banu, Carmen Chifiriuc, Dan Mihaiescu, Paul Balaure, Veronica Lazar: Biocompatible magnetic MWCNTs based on phytocomponents from Eugenia carryophyllata.Revista de Chimie (Bucharest), 63(5), 2012.
The aim of the present study was the phytocomponents extraction from the aromatic waters of Eugenia carryophyllata by magnetic MWCNT encapusaltion, in order to obtain biocompatible nanoparticles with clinical applications. Eugenia carryophyllata dried buds were hydrodistilled, in microwave conditions, using a Neo-Clevenger device. The aqueous residue was separated in two equal parts, one for the chloroform extraction and the other for the extraction with magnetic MWCNT. The chemical composition of the aqueous residue extracts was established by GC-MS analyses. The high content of eugenol and α-cariophyllen was proven in both magnetic MWCNT assisted and chloroform extraction. The MWCNT antimicrobial activity was tested against 20 Staphylococcus aureus strains. The MIC value for all tested strains was 50mg/mL, smaller concentrations being promoters for bacterial growth probably due to the large surface offered by MWCNT for microbial adherence and to the subinhibitory concentration of encapuslated phytocomponents with antimicrobial activity.